Taking NMN: Comprehensive Protection for Heart Health!

Heart health is one of the critical global topics in 2024, with millions of people dying each year from heart disease and its related causes. AIDEVI is vigorously researching NMN in hopes of finding ways to delay additional complications caused by heart disease, slow down heart aging, and empower the heart.

Aging, the Culprit of Cardiovascular Disease

Cardiovascular disease poses a significant threat to human health. Despite the implementation of various effective and safe prevention strategies worldwide, cardiovascular disease remains a leading cause of global mortality and premature death. These health issues predominantly emerge in old age, closely linked fundamentally to the body's aging process despite factors such as diet and lifestyle.

Moreover, amid the global COVID-19 pandemic, data from multiple countries have shown that the elderly and those with underlying health conditions have become the most vulnerable groups, exhibiting increased susceptibility, severity of illness, and higher mortality rates. This underscores the importance of strengthening chronic disease management. Adhering to medical advice, consistent medication use, standardized disease management, and controlling cardiovascular disease risk factors are crucial in reversing the severe trend of cardiovascular disease incidence in our country.

A Healthy Heart Makes You Younger

NAD+ (Nicotinamide Adenine Dinucleotide), as a coenzyme involved in many crucial biochemical reactions in our bodies, plays a vital role in maintaining normal mitochondrial function. An important mechanism underlying heart aging and related diseases is mitochondrial dysfunction. Mitochondria not only serve as the primary source of energy (ATP) for the heart but also play a crucial role in the survival of cardiac muscle cells. Due to the heart's limited ATP reserves, robust and uninterrupted mitochondrial function is necessary to provide ATP continuously to maintain heart function; otherwise, it may lead to conditions such as heart failure.

Furthermore, the ratio of NADH/NAD+ is closely associated with heart health. NADH is the reduced form of NAD+, and the NADH/NAD+ ratio is a critical factor in cellular signal transduction. Studies have found a significant increase in the NADH/NAD+ ratio in the failing human heart. In other words, increasing NAD+ levels helps decrease this ratio.

NMN: Comprehensive Protection for Heart Health

Since the level of NAD+ in the heart is crucial, is increasing NAD+ levels beneficial? Multiple studies have shown that using the NAD+ precursor NMN (Nicotinamide Mononucleotide) can improve the NAD+ homeostasis of the heart, alleviate age-related cardiac pathological and physiological changes. Furthermore, clinical trials on NMN have shown promising results, confirming its safety and efficacy.

1. Protecting the Heart from Ischemia/Reperfusion Injury

Aging significantly increases the occurrence of ischemia/reperfusion injury, while increasing NAD+ levels in the heart can have a positive impact. In 2014, researchers at the New Jersey Medical School found that intraperitoneal injection of NMN in mice significantly increased NAD+ levels in the heart and prevented a decrease in NAD+ during ischemia, thus protecting the heart from ischemia/reperfusion injury.

2. Maintaining Cardiac Mitochondrial Homeostasis to Prevent Heart Failure

The reduced activity of NAD+ and its mediated Sirtuins negatively affect mitochondrial function, which is a key mechanism in the pathogenesis of heart disease.

3. Improving the Metabolism and Function of Aging Hearts

In 2020, a study from the University of Washington tested the effects of two different mitochondrial-targeted drugs, SS-31 (a synthetic tetrapeptide) and NMN, and found that SS-31 partially reversed age-related diastolic dysfunction, while NMN completely reversed age-related cardiac systolic dysfunction. The synergistic effect of both can better rejuvenate aging hearts.

4. Alleviating Cardiac Fibrosis

Several factors such as atherosclerosis, cardiac metabolic abnormalities, myocardial ischemia, etc., can lead to cardiac fibrosis, resulting in abnormal stiffness and eventual heart failure.

Supplementing NMN also has excellent protective effects on blood vessels, reducing cardiovascular diseases, improving heart disease, and vascular dysfunction. NMN intake can restore the activity of Sirt1 in blood vessels, delay the decline in the number and function of endothelial cells, and improve endothelial dysfunction and large elastic arterial sclerosis caused by aging.

Numerous studies have confirmed the excellent protective effects of NMN supplementation on heart disease and blood vessels. NMN effectively revitalizes the cardiovascular system, playing a significant role in the prevention and treatment of cardiovascular and cerebrovascular diseases.

Here are some strategies for preventing cardiovascular and cerebrovascular diseases:

1. Adjust clothing according to temperature changes, maintain indoor warmth, and avoid rapid temperature changes.

2. Exercise appropriately to enhance resistance. The amount of exercise varies from person to person, avoiding excessive activity, and avoiding exercising in polluted environments.

3. Maintain a light diet, choose a low-salt, low-fat, high-fiber diet, and keep bowel movements regular (spring exacerbates constipation, which is also a major cause of angina pectoris).

4. Pay attention to room ventilation and avoid respiratory infections.

5. Seek medical attention promptly if symptoms such as chest tightness or chest pain occur.

AIDEVI NMN18000 is a safe choice that can effectively delay the onset of heart disease and prevent various additional complications. Additionally, NMN18000 can reinvigorate the heart's blood supply capabilities, ensuring lasting clarity. It is recommended to purchase authentic NMN from the official AIDEVI store!